Chiara Gamberi

Affiliate Assistant Professor, Concordia University

Developmental biology, disease models, drosophila (fruit flies), RNA biology, mRNA translation

Media

What's the latest on gut microbiota? Concordia microbiology undergrads publish their findings

Une chercheuse de Concordia dirige une équipe de 94 étudiants au premier cycle dans le cadre d'une étude sur la santé intestinale

Researcher leads a team of 94 undergrads to explore gut health

Concordia researcher leads a team of 94 undergrads to explore gut health

Biography

After completing her studies in Italy and at the EMBL Heidelber (Germany), Chiara Gamberi became an international scientist in the US and then found a new home in Canada.

The Gamberi laboratory studies the spatio-temporal regulation of messenger (m) RNA translation and its effects on cell and organismal polarization in normal homeostasis and disease employing the genetically tractable model of the fruit fly Drosophila melanogaster. 75% of human disease-related pathways are conserved in flies, yet the complexity of the human and vertebrate anatomy and physiology often hinders studies of the underpinning genetics and molecular biology, which limits our ability to design effective therapeutics. While using fruit flies to study human physiology may seem unlikely at first glance, the extensive evolutionary conservation can be leveraged to design highly informative studies. In fact, many fundamental and complex biological processes have been first discovered in flies (e.g., chromosomes are the base of inheritance, X-rays mutagenicity, circadian rhythms, stem cells etc.).

Her lab's interdisciplinary research in molecular developmental biology utilizes genetic, molecular and chemical screens to advance mechanistic knowledge of pathological states (e.g., cystic kidneys) and longevity-promoting pathways to identify therapeutic approaches.

Expertise

  • developmental biology
  • disease models
  • drosophila (fruit flies)
  • RNA biology
  • mRNA translation

Education/Éducation

  • University of Verona
    PhD